The connecting record
shownBoruto: Naruto Next Generations · 2021
Naruto Uzumaki killed Isshiki Otsutsuki in Boruto: Naruto Next Generations.
shared — Baryon Mode cut his lifespan, Kawaki struck last
What each of them is ranked on
The killer · Naruto Uzumaki · rank 5
The Seventh Hokage — shippuden
Inside Baryon Mode he outfights the strongest thing the sequel has produced, and the argument for fifth rather than first is what that costs: the form burns his own life to run, expires on a clock, and leaves somebody else to strike last. He also spent the entire series formally ranked genin — the lowest grade the system issues — and then became Hokage, the top of the same ladder, without passing the examination in between.
shownBoruto: Naruto Next Generations · Isshiki arc
Enters Baryon Mode and outfights Isshiki at the cost of his own lifespan. — 2021
statedNaruto · Konoha Crush arc
His promotion ceremony is interrupted and never rescheduled. — 2002
shownNaruto · Kaguya arc
Fights Kaguya alongside Sasuke in Six Paths Sage Mode. — 2014
The victim · Isshiki Otsutsuki · rank 1
Jigen — boruto
He handles the two strongest shinobi alive at once and is not seriously troubled by it, which nothing else in the franchise manages. What finally works against him is not better fighting but a form that runs on its user's remaining life: inside Baryon Mode, Naruto does outpace and outhit him — and then the mode expires on schedule, having shortened Isshiki's lifespan enough for somebody else to land the last blow. First place here belongs to the opponent nobody beat with a technique they could use twice.
shownBoruto: Naruto Next Generations · Isshiki arc
Overwhelms Naruto and Sasuke together before Baryon Mode is used. — 2021
shownBoruto: Naruto Next Generations · Isshiki arc
Outfought by Baryon Mode, then ends it by stomping Naruto out of the form rather than by outlasting it. — 2021
What this does not settle
One death in one work. It is the only place the record puts these two in the same room, and it is evidence about that meeting and nothing wider — not a general matchup, not a rematch, and not a ranking of its own.
The ladder above it is argued from everything either of them has been shown doing; this page is argued from one citation.
Where the two disagree, the disagreement is the point, and it stays visible rather than being resolved by whichever of them happens to be on this page.